HealthAugust 4, 2026

corticosterone

KOR-tih-ko-STEER-ohn

Definition

A steroid hormone secreted by the adrenal glands that serves as the primary stress hormone in rodents.

Etymology

Derived from 'cortex' (referring to the adrenal cortex) plus 'sterone' (indicating it is a steroid hormone). It was first identified in the mid-20th century as a critical regulator of metabolic and stress responses.

In the news

In this study, the researchers found that corticosterone acts as a key messenger that triggers brain immune cells in female mice to rewire neural connections after anesthesia.

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