HealthAugust 13, 2026
electrophilic
eh-LEK-truh-FIL-ik
Definition
Describes a chemical species that is attracted to electrons and capable of forming bonds by accepting an electron pair from a nucleophile.
Etymology
Derived from the Greek words 'elektron' (amber) and 'philos' (loving). The term was coined in chemistry to describe substances that 'love' or seek out electron-rich sites in other molecules.
In the news
In this article, electrophilic stress refers to chemical conditions that modify specific reactive proteins like KEAP1, which in turn influences the activation of the NRF2 antioxidant pathway.
How Obesity Triggers Cellular Stress Through Unfolded Protein Response and NRF2 Signaling
Read the full article ↗Bioengineer.org