HealthAugust 11, 2026

integrin

IN-tuh-grin

Definition

A type of transmembrane receptor protein that facilitates cell-extracellular matrix (ECM) adhesion and plays a critical role in cellular signaling and tissue repair.

Etymology

Coined in 1986 by American biologist Richard Hynes, the term is a portmanteau derived from 'integrated' and 'protein,' reflecting the protein's role in integrating the cellular cytoskeleton with the extracellular matrix.

In the news

The article discusses integrins as the specific biological targets for Pliant Therapeutics' pipeline of small-molecule drugs designed to treat fibrotic diseases.

Pliant Therapeutics Provides Corporate Update and Reports Second Quarter 2026 Financial Results

Read the full article ↗

The Manila Times

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