HealthAugust 4, 2026

ligand

LY-gund

Definition

A molecule that binds to another specific molecule, such as a protein, to form a complex and trigger a biological response.

Etymology

Derived from the Latin word 'ligare,' meaning 'to bind.' It entered scientific terminology in the 20th century to describe molecules that connect to larger biological structures.

In the news

The article discusses the PD-L1 ligand, which is a protein that acts as an 'inhibitory checkpoint' to suppress immune activity; the drug works by blocking this ligand to restore immune function.

Phase 1 Trial Validates Anti-PD-L1 Antibody for Alzheimer’s

Read the full article ↗

Neuroscience News

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