ScienceSeptember 2, 2026

metalloproteinases

muh-TAL-oh-PRO-tuh-nay-siz

Definition

Enzymes that break down proteins and require a metal ion, such as zinc, to function; in snake venom, these enzymes cause tissue damage and bleeding.

Etymology

The word is a combination of 'metallo-', referring to a metal ion, and 'proteinase', an enzyme that breaks down proteins. It emerged in the 20th century within the field of biochemistry to describe these specific metal-dependent enzymes.

In the news

The article highlights these enzymes as specific toxic proteins in pit viper venom that standard antivenoms fail to neutralize, leading to severe internal damage.

Same Bite, Same Hospital, Different Odds — Depending on Which Snake Found You

Read the full article ↗

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