WorldAugust 27, 2026

sacubitril

suh-KYOO-bih-tril

Definition

A neutral endopeptidase inhibitor (NEPi) used as an active ingredient in combination therapy to treat heart failure.

Etymology

Sacubitril is a non-proprietary drug name created using standard pharmacological naming conventions, specifically incorporating syllables to designate its chemical class and function as an inhibitor.

In the news

In the article, sacubitril is one of the two active pharmacological ingredients in the heart failure drug Entresto; the patentability of this specific combination was the core subject of the legal dispute.

A 'close call' on plausibility: Patents Court finds Novartis' Entresto patent application sufficient in Accord's UK revocation challenge

Read the full article ↗

Mishcon de Reya LLP

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