superoxide
SOO-per-ock-side
Definition
A highly reactive oxygen species (ROS) containing an extra electron, which functions as a signaling molecule at low levels but can cause significant cellular damage when produced in excess.
Etymology
The term is a combination of the Latin 'super-' meaning 'above' or 'over,' and 'oxide,' denoting a compound of oxygen with another element. It describes an oxide with a higher proportion of oxygen than typical counterparts.
In the news
In the article, superoxide is identified as one of the chemically reactive molecules generated by mitochondrial stress during overnutrition. Its accumulation is a key driver of oxidative stress that interferes with cellular health.
How Obesity Triggers Cellular Stress Through Unfolded Protein Response and NRF2 Signaling
Read the full article ↗Bioengineer.org