edotreotide
eh-doh-TREE-oh-tide
Definition
A synthetic radioactive compound (often tagged with Lutetium-177) designed to target and bind to somatostatin receptors on the surface of certain neuroendocrine tumor cells.
Etymology
The name is a technical construction derived from 'edot' (referring to a specific chelating structure) and 'reotide' (a suffix common to octreotide-based somatostatin analogs, which are peptide chains that mimic natural hormones).
In the news
In this article, 177Lu-edotreotide is the specific radioligand therapy under review by the FDA for the treatment of gastroenteropancreatic neuroendocrine tumors. The drug's approval was delayed not because of its clinical success, but due to manufacturing and facility-related inspections.
FDA Does Not Approve 177Lu-Edotreotide for GEP-NETs
Read the full article ↗Targeted Oncology