HealthAugust 11, 2026

granzyme

GRAN-zaime

Definition

A type of protein-digesting enzyme released by certain immune cells to induce programmed cell death in target cells, such as tumor cells.

Etymology

Derived from a combination of the words 'granule' (referring to the small particles where these enzymes are stored in immune cells) and 'enzyme' (a biological catalyst).

In the news

The article mentions granzyme-B as a marker for cytotoxic arming in patients who responded positively to the drug PLN-101095, indicating that the patient's immune system is successfully targeting the tumor.

Pliant Therapeutics Provides Corporate Update and Reports Second Quarter 2026 Financial Results

Read the full article ↗

The Manila Times

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