mutein
MYOO-teen
Definition
A protein that has been genetically engineered or modified to possess a specific amino acid change that alters its function or properties.
Etymology
The word is a portmanteau derived from 'mutant' and 'protein'. It was coined to specifically describe proteins created through targeted genetic mutation rather than random mutation.
In the news
The article uses the term to describe an engineered version of the protein IL-18 that is designed to specifically bind to a receptor while avoiding decoy inhibitors. This modification is key to the therapeutic efficacy of the company's FL116 drug candidate.
Forlong Biotechnology Announces Successful Completion of GMP Pivotal Batch Production for FL115 (IL-15 Superagonist), Ready to Support Upcoming Phase III Clinical Trial in Non-Muscle Invasive Bladder Cancer (NMIBC)
Read the full article ↗BioSpace