HealthAugust 18, 2026

naltrexone

nal-TREK-sohn

Definition

A pharmacological agent identified in the systematic review as one of the few medications that has been studied across all stages of the research pipeline for methamphetamine use disorder.

Etymology

The name is a portmanteau derived from its chemical structure: 'nal' from the n-allyl group and 'trexone' derived from the opioid antagonist naltrexone's relationship to oxymorphone, a synthetic opioid.

In the news

The article lists naltrexone as one of the rare medications that has undergone systematic evaluation in preclinical, human laboratory, and clinical research settings for treating stimulant use.

Graduate researcher leads landmark methamphetamine treatment systematic review

Read the full article ↗

Medical Xpress

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