HealthAugust 4, 2026

superagonist

SOO-per-AG-uh-nist

Definition

A compound that binds to a receptor and triggers a biological response stronger or more effective than the natural signaling molecule (agonist).

Etymology

Derived from the Latin 'super' (above or beyond) and the Greek 'agonistes' (a combatant or actor), reflecting its role as a molecule that 'acts' more powerfully than the standard receptor ligand.

In the news

In this article, the term describes the drug FL115, which is engineered to be a more potent version of the natural immune signaling protein IL-15.

Forlong Biotechnology Announces Successful Completion of GMP Pivotal Batch Production for FL115 (IL-15 Superagonist), Ready to Support Upcoming Phase III Clinical Trial in Non-Muscle Invasive Bladder Cancer (NMIBC)

Read the full article ↗

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