HealthSeptember 4, 2026

zilganersen

ZIL-guh-nur-sen

Definition

An antisense oligonucleotide drug developed by Ionis Pharmaceuticals to treat the underlying cause of the rare neurodegenerative disorder known as Alexander disease.

Etymology

The name is a modern pharmaceutical coinage following standard naming conventions for drugs, where the suffix '-ersen' identifies it as an antisense oligonucleotide.

In the news

Zilganersen is introduced as the specific therapeutic agent that has received FDA approval as a disease-modifying treatment for patients with Alexander disease.

Ionis nets Zanvastro US approval in first for Alexander disease

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Pharmaceutical Technology

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